Buy AOD-9604 5mg Research Peptide OnlineAOD-9604 is a 16-amino-acid synthetic peptide derived from the C-terminal sequence of human growth hormone. The peptide preserves the lipolytic domain of native GH while removing growth-promoting epitopes, creating a research tool for investigating lipid mobilization pathways in preclinical adipocyte models.AOD-9604 Structural Design & MechanismThe C-terminal region of growth hormone (amino acids 177-191) contains the lipolytic activity site responsible for triglyceride hydrolysis. AOD-9604 incorporates this region with a D-alanine substitution (position 2) to enhance proteolytic stability in cell culture media. Preclinical research in adipocyte models demonstrates activation of hormone-sensitive lipase (HSL) and increased free fatty acid release without engaging classical GH receptor signaling pathways.AOD-9604 Peer-Reviewed Preclinical EvidenceJournal of Endocrinology (2004) reported AOD-9604 stimulation of lipolysis in isolated rat adipocytes and cultured human fat cells, showing dose-dependent increases in glycerol and FFA release. Obesity (2010) characterized the peptide’s metabolic profile in differentiated 3T3-L1 adipocytes, documenting elevated PKA activation and phosphorylation of perilipin. International Journal of Obesity (2013) examined specificity, confirming lipid-mobilization effects without growth hormone-like proliferative signaling.AOD-9604 Research ApplicationsCommonly used in adipocyte differentiation and lipolysis assays, metabolic screening protocols, and tissue culture models of lipid handling. Researchers apply AOD-9604 to study hormone-sensitive lipase regulation, cAMP-PKA signaling, and fat oxidation in laboratory settings.AOD-9604 5mg Product SpecificationsSupplied as 5mg lyophilized peptide powder. Store at -20°C in sealed, desiccated vials. Purity ≥97% by HPLC/MS. Reconstitution in sterile saline or PBS (1-5 mg/mL) recommended. Typical research concentration: 0.1-1 μM in cell culture.AOD-9604 Research Use Only DisclaimerThis product is intended exclusively for in vitro preclinical research. Not suitable for human consumption, clinical application, or in vivo animal studies. All use must comply with institutional biosafety and chemical safety guidelines.
