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S4 (Andarine) is a Selective Androgen Receptor Modulator (SARM). The development of this substance exhibits tissue-selective androgen receptor modulation at myogenic and osseous sites. S4 preferentially binds to androgen receptors, perhaps initiating anabolic transcriptional signaling pathways while limiting activity in non-target organs. It is considered less potent than other SARMs, but this is investigated for its balance between potential improvements in contractile performance metrics and reduced off-target pharmacodynamic responses. Since this is a SARM, it is strictly intended for laboratory research use and is not approved for human or veterinary applications. Mechanism of Action In preclinical research, S4 (Andarine) is studied for its selective interaction with androgen receptors in skeletal muscle and bone tissues. In the binding process, it may activate intracellular signaling pathways associated with protein synthesis and muscle tissue development, mTOR-regulated anabolic gene expression, and bone matrix turnover and mineralization processes Properties of S4 Andarine Chemical Formula: C19H18F3N3O6 Molar Mass: 441.363 g/mol CAS Number: 401900-40-1 IUPAC Name: (2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide Synonyms: Andarine; S4; Acetamidoxolutamide; Androxolutamide; GTx-007 Research Applications Muscle Tissue Research Studies look at how S4 interacts with pathways related to protein regulation and muscle structure. It is used to observe how selective receptor activation may influence measurable changes in muscle-related parameters under controlled conditions. [2] Skeletal Research S4 is also included in studies involving bone signaling processes. This includes research on matrix turnover and mineralization, helping to examine structural changes in experimental models. [3] Partial Agonist Activity Andarine S4 shows partial agonist behavior, meaning it does not fully activate the receptor. This allows researchers to study different levels of receptor response and how these levels affect cellular activity. [1] Comparative Research S4 is often compared with other SARMs to observe differences in selectivity, potency, and signaling behavior. These comparisons support research into the relationships between structure and function. [2] Why Choose Behemoth Labz to Buy Andarine? For researchers looking for a consistent source of S4 Andarine for laboratory use, Behemoth Labz may give both liquid and capsule options for better scientific work. Behemoth Laz focuses on maintaining product quality with the best handling standards Behemoth Labz has built a record of reliability through consistent order processing and customer support. You can talk to them anytime at
[email protected] | (307) 429-0990. Disclaimer: This information is for educational purposes. We do not allow the human consumption of our products. All our products are sold for laboratory and research experiments. References Narayanan, Ramesh, et al. “Selective androgen receptor modulators in preclinical and clinical development.” Nuclear Receptor Signaling 6 (2008): e010. Dalton, James T., et al. “The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function.” Journal of Cachexia, Sarcopenia and Muscle 2.3 (2011): 153–161. Basaria, Shehzad. “Selective androgen receptor modulators: current status and future perspectives.” Endocrinology and Metabolism Clinics 39.1 (2010): 163–179.
