Buy 5 AMINO 1MQ 10mg for Research OnlineThis compound represents a highly potent cell-penetrant NNMT antagonist studied extensively in preclinical metabolic models. The quinolinium derivative crosses cellular membranes efficiently, enabling investigation of intracellular NAD and methylation dynamics in research settings without requiring transfection or specialized delivery systems.5 AMINO 1MQ Biochemical Activity ProfileNNMT catalyzes the methylation of nicotinamide to N1-methylnicotinamide using S-adenosyl methionine (SAM) as cofactor. This inhibitor disrupts that pathway in laboratory cell cultures, creating an essential research tool for studying energy metabolism and epigenetic processes at the preclinical level. IC50 values in the nanomolar range confirm exceptional potency in enzyme inhibition assays.5 AMINO 1MQ Literature FoundationResearch published in Cell Metabolism (2020) examined NNMT’s contribution to metabolic reprogramming in cultured cancer cell lines, demonstrating altered glucose utilization and NADH/NAD ratios when the enzyme was inhibited. Additional studies in Science Translational Medicine (2022) characterized the compound’s specificity and binding kinetics using biochemical assays and X-ray crystallography of the enzyme-inhibitor complex.5 AMINO 1MQ 10mg Formulation & HandlingSupplied as 10mg lyophilized powder. Stable at -20°C for 24 months when maintained in dry, sealed containers. Compatible with DMSO and standard aqueous buffers for cell culture applications. Recommended concentration range: 1-50 μM in vitro. Solubility in cell culture media supports direct addition to live cell systems.5 AMINO 1MQ 10mg Quality Assurance & SpecificationsPurity ≥98% by HPLC/MS. Endotoxin-tested and suitable for sensitive cell culture applications. Compatible with automated screening protocols.5 AMINO 1MQ Research Use Only DisclaimerThis product is intended solely for laboratory research and preclinical experimentation. Not approved for human use, clinical trials, or in vivo administration. Researchers must follow institutional guidelines for chemical safety and waste disposal.
