Buy 5 AMINO 1MQ 5mg for Research OnlineThis selective small-molecule compound targets nicotinamide N-methyltransferase (NNMT), a critical metabolic enzyme regulating NAD and polyamine homeostasis in preclinical models. The quinolinium-based structure demonstrates superior cellular permeability compared to earlier-generation NNMT inhibitors, facilitating efficient investigation in laboratory settings.5 AMINO 1MQ Molecular Classification & MechanismThe compound acts as a competitive inhibitor of NNMT, modulating methylation pathways essential to energy metabolism in cultured cell systems. Preclinical studies in adipocyte and muscle tissue models indicate dose-dependent effects on mitochondrial function and intracellular NAD cycling. The inhibitor reduces N1-methylnicotinamide (MNA) production, enabling accumulated cellular NAD pools in research conditions.5 AMINO 1MQ Preclinical Research ContextPublished research in Molecular Metabolism (2019) demonstrated NNMT inhibition in cultured hepatocytes resulted in enhanced cellular respiration rates and altered lipid composition. A subsequent study in Nature Communications (2021) explored NNMT’s role in metabolic regulation across multiple cell types, establishing the compound’s mechanism of action in laboratory settings. These studies confirm target specificity and reproducible dose-response relationships.5 AMINO 1MQ 5mg Technical Specifications & HandlingSupplied as lyophilized powder (5mg per vial). Store at -20°C in desiccated sealed containers. Reconstitution with sterile water or bacteriostatic saline recommended for in vitro protocols. Solubility approximately 10-15 mg/mL in standard laboratory buffers (PBS, DMEM). Purity ≥98% by HPLC analysis. Stable minimum 24 months at -20°C.5 AMINO 1MQ Research Use Only DisclaimerThis product is intended exclusively for in vitro research and preclinical investigation. Not suitable for human consumption, clinical use, or therapeutic application. All handling must comply with institutional laboratory safety protocols and chemical waste disposal guidelines.
