Buy Melanotan 1 Acetate (MT-1) 10mg Research Peptide OnlineMelanotan 1 Acetate (afamelanotide) comprises a synthetic peptide developed as a selective melanocortin-1 (MC1R) receptor agonist for preclinical investigation of pigmentation physiology and melanocyte signaling. This cyclic alpha-melanocyte stimulating hormone analog has served as a research tool in dermatological science examining MC1R-dependent cellular responses.Melanotan 1 Acetate (MT-1) 10mg Product Specifications & StorageThe 13-amino acid peptide backbone incorporates cyclization through a disulfide bridge between N-terminal and C-terminal cysteine residues, conferring enhanced metabolic stability compared to linear melanocortins. This structural modification extends functional activity in cellular assays through protease resistance.Melanotan 1 Acetate (MT-1) Mechanism of ActionBinding affinity studies employ melanoma cell lines and transfected HEK293 cells expressing recombinant human MC1R. Radioligand competition assays document Melanotan 1 IC50 values in nanomolar concentration ranges, demonstrating selective engagement with MC1R over related melanocortin receptor subtypes (MC3R, MC4R, MC5R).Cellular signaling investigations measure cAMP accumulation in MC1R-transfected cells following Melanotan 1 exposure, establishing functional agonist capacity through G-protein coupled receptor activation. Downstream effects on melanin synthesis pathways are measurable through quantitative analysis of cellular pigmentation and tyrosinase activity in primary melanocyte cultures.Our Melanotan 1 Acetate supply provides 10mg per vial as lyophilized powder with >97% purity verified through HPLC and mass spectrometry. The acetate salt formulation enhances aqueous solubility compared to free peptide base.Reconstitute in sterile water or PBS for cellular applications; store lyophilized material at -20°C for extended stability (24 months). Reconstituted solutions maintain activity at 4°C for 14 days under sterile conditions.Melanotan 1 Acetate is supplied exclusively for research applications in academic and commercial laboratory settings. This compound is not approved for human administration, dermatological treatment, or cosmetic application. All usage must comply with institutional biosafety regulations and animal care standards where applicable.
