Description Avanafil Avanafil is a phosphodiesterase-5 enzyme (PDE-5) inhibitor, meaning it blocks PDE-5. A recent randomized control study found Avanafil to be superior to sildenafil in improving the International Index of Erectile Function. Avanafil CAS Number 330784-47-9 Molar Mass 483.95g/mol Chemical Structure C23H26CIN7O3 IUPAC Name 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
